2,6-difluoro-3-[(propylsulfonyl)aMino]Benzoic acid
2,6-Difluoro-3-[(propylsulfonyl)amino]benzoic acid
CAS: 1103234-56-5
Molecular Formula: C10H11F2NO4S
2,6-difluoro-3-[(propylsulfonyl)aMino]Benzoic acid - Names and Identifiers
2,6-difluoro-3-[(propylsulfonyl)aMino]Benzoic acid - Physico-chemical Properties
| Molecular Formula | C10H11F2NO4S |
| Molar Mass | 279.26 |
| Density | 1.518 |
| Melting Point | 205～208℃ |
| Boling Point | 394.5±52.0 °C(Predicted) |
| pKa | 2.11±0.10(Predicted) |
| Storage Condition | Sealed in dry,Room Temperature |
| Sensitive | Irritant |
| MDL | MFCD18157658 |
| Use | Use Only Rofini (Vemurafenib) is a BRAF inhibitor approved in FDA2011 in the United States. It is mainly used for the treatment of advanced melanoma. Clinical studies have shown that the drug resistance of Verofenib is more prominent, and the condition is relieved in the first few months of application to patients. |
2,6-difluoro-3-[(propylsulfonyl)aMino]Benzoic acid - Upstream Downstream Industry
| Downstream Products | 1-PropanesulfonaMide, N-[3-[[5-broMo-1-(2,6-dichlorobenzoyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]- |
2,6-difluoro-3-[(propylsulfonyl)aMino]Benzoic acid - Overview
Vemurafenib is a BRAF inhibitor approved by the United States in FDA2011. It is mainly used for the treatment of advanced melanoma. Clinical studies have shown that the drug resistance of Verofenib is more prominent, and the condition is relieved in the first few months of application. However, in most cases, melanoma recurs in the following months. Therefore, it is gradually necessary to find verafenib sensitizers. Researchers in the industry have paid attention to the efficacy of verafenib. Some studies have found that phenformin has a sensitizing effect on verafenib. As a verafenib sensitizer; there are studies looking for verafenib sensitizer from natural drugs. The only Ro Fini intermediate is 2, 6-difluoro-3-(propylsulfonamide) benzoic acid, which is mainly used to synthesize Ro Fini
Last Update：2024-04-09 20:52:54
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Product Name: 2,6-Difluoro-3-(propylsulfonamido)benzoic acid Visit Supplier Webpage Request for quotation
CAS: 1103234-56-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 1103234-56-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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